Dan Deng

Dan Deng, M.D. Ph.D. Email: [email protected], MP: 008618018527652 Vice President of CTRS (Chinese Tissue Repair Society) Director of the Department of Dermatology, Shanghai Children's Medical Center (National Children's Medical Center) affiliated with the Shanghai Jiaotong University School of Medicine. Dr. Deng brings a rare and distinguished combination of expertise in both plastic & dermatologic surgery and skin tissue engineering — a background that uniquely positions her as a leader in pediatric dermatologic care. Dr. Deng began her medical career in plastic and reconstructive surgery, training and working at the prestigious Department of Plastic Surgery at Shanghai 9th People’s Hospital from 2003 to 2012, meanwhile work at the Tissue Engineering Key Laboratory of Shanghai. She then transitioned to dermatology, furthering her training and clinical practice in the Department of Dermatology at Xinghua Hospital from 2013 to 2022. Both institutions are internationally recognized teaching hospitals affiliated with Shanghai Jiaotong University School of Medicine. With over two decades of clinical experience, Dr. Deng has developed deep expertise in the surgical and non-surgical management of complex skin disorders in children. Her dual specialty training in plastic surgery and dermatology is exceedingly rare and places her among a select group of physician-surgeons worldwide capable of bridging aesthetic, functional, and dermatologic concerns in pediatric patients. Dr. Deng is deeply committed to medical education, clinical excellence, and advancing multidisciplinary care in dermatology. Under Dr. Deng’s visionary leadership, the Department of Dermatology at Shanghai Children’s Medical Center has evolved into a nationally recognized center of excellence in the diagnosis, treatment, and research of pediatric skin diseases. The department now serves as a referral hub for complex pediatric dermatologic conditions from across China and beyond, offering advanced care for a wide spectrum of disorders, including keloid disorder, vascular anomalies, genodermatoses, inflammatory skin diseases, pediatric tumors, and post-surgical skin reconstruction. Her interests include treating birthmarks such as giant congenital melanocytic nevi, Mohs’ surgery, managing wounds in patients with epidermolysis bullosa (EB), and cosmetic surgery. She believes and promotes the idea of “less pain by comfortable anesthesia and pain control, and less damage from the donor site by divided surgery and repair with a local flap or artificial skin graft combined with a negative pressure system." One of her surgical methods for recessive dystrophic epidermolysis bullosa (RDEB) syndactyly release has been published by JAAD and recommended to be complementary of the current guidelines on hand surgery management of patients with EB. Serving as a Committee member of Debra-China, Dr. Deng leads the biggest RDEB Pseudosyndactyly Release Surgery and Wound Healing center in china and has helped more than 100 RDEB patients not only for hand surgery, but also laser treatment and cell transplantation for wound healing, as well as treatment of EB tumor such as SCC, spitz nevus etc. In addition, Dr. Deng’s team has devoted to exploring gein therapy such as through-reading treatment with gentamicin for RDEB patients nonsense mutation, non-viral delivery of COL7A1 gene segments by Piggy-bac transposon of allogenic fibroblasts. Dr. Deng has championed a multidisciplinary approach, integrating dermatology with pediatrics, surgery, oncology, and genetics to provide holistic and individualized care. Under her guidance, the department has adopted state-of-the-art technologies, including laser therapies, dermatologic imaging, and minimally invasive surgical techniques, establishing new standards for pediatric dermatologic care not only in Shanghai, but also in the region. In addition to its clinical mission, the department has also become a leading academic and training center, mentoring the next generation of pediatric dermatologists and dermatologic surgeons. It plays an active role in national research initiatives and regularly contributes to peer-reviewed publications, clinical trials, and international collaborations focused on advancing the science and practice of pediatric dermatology.